abstract：:Disseminated histoplasmosis (DH) is a systemic granulomatous disease caused by the fungus Histoplasma capsulatum. This disease occurs mainly in immunocompromised individuals with CD 4 counts less than 200 cell/µL and is rarely noted in immunocompetent person. In India, this disease has been reported from several parts...

journal_title：Diagnostic cytopathology

authors： Kumari M,Udayakumar M,Kaushal M,Madaan GB

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:We previously found that the presence of atypical urothelial tissue fragments (AUTF) was associated with an increased risk of high-grade urothelial carcinoma (HGUC) but not low-grade urothelial neoplasia (LGUN) in voided urine (VU) specimens. However, we subsequently found that patients with LGUN were more l...

journal_title：Diagnostic cytopathology

authors： Zhang ML,Zhou AG,Rosenthal DL,VandenBussche CJ

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:The use of fine-needle aspiration (FNA) cytology for the preoperative evaluation of salivary gland lesions is an accepted but, currently, nonstandardized practice. More specifically, cystic major salivary gland lesions are relatively rare and can be very challenging to diagnose on FNA due to low cellularit...

journal_title：Diagnostic cytopathology

authors： Allison DB,McCuiston AM,Kawamoto S,Eisele DW,Bishop JA,Maleki Z

更新日期：2017-09-01 00:00:00

abstract：:We report one case of metastatic synovial sarcoma (SS) to the parotid gland in a 93-year-old male. The patient had undergone upper left pulmonary lobectomy with mediastinal lymphadenectomy for SS of the lung 5 years before. The cytopathologic presentation and the immunocytochemical findings on the FNA sample were sugg...

journal_title：Diagnostic cytopathology

authors： Fulciniti F,Barizzi J,Martin V,Tarallo V,Ermanni S

更新日期：2017-09-01 00:00:00

abstract：:Warthin-like papillary thyroid carcinoma (WLPTC) is a rare morphological variant of papillary thyroid carcinoma which mimics various benign and malignant lesions on thyroid aspiration cytology. As correct cytological diagnosis is the cornerstone for appropriate patient management, awareness of the salient cytomorpholo...

journal_title：Diagnostic cytopathology

authors： Vallonthaiel AG,Agarwal S,Jain D,Yadav R,Damle NA

更新日期：2017-09-01 00:00:00

abstract：:Ocular medulloepithelioma (ME) is a rare congenital tumor which occurs usually during childhood but is also reported in adults. They have seen an intraocular tumor in an 89 years-old female with a history of small cell lung carcinoma. Transscleral fine needle aspiration was performed. Aspirates were rich and composed ...

journal_title：Diagnostic cytopathology

authors： Mahdjoubi A,Cassoux N,Levy-Gabriel C,Desjardins L,Klos J,Caly M,Vlajnic T,Gardrat S,Klijanienko J

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) offers a six-tiered diagnostic scheme for thyroid Fine Needle Aspiration (FNA): Benign, Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance (AUS/FLUS), suspicious for follicular neoplasm, suspicious for malignancy...

journal_title：Diagnostic cytopathology

authors： Padmanabhan V,Marshall CB,Akdas Barkan G,Ghofrani M,Laser A,Tolgay Ocal I,David Sturgis C,Souers R,Kurtycz DF

更新日期：2017-05-01 00:00:00

abstract：:Pleomorphic xanthoastrocytoma (PXA) is a WHO grade II astrocytic tumor of children and young adults. It is characterized by pleomorphic, atypical astrocytes. Atypia is so remarkable, that PXA can be easily misdiagnosed as malignant glioma. If confused with a high-grade glioma the neurosurgeon may not proceed with a co...

journal_title：Diagnostic cytopathology

authors： Jiménez-Heffernan JA,Freih Fraih A,Álvarez F,Bárcena C,Corbacho C

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The Afirma gene expression classifier (GEC) is being increasingly utilized to confirm the benign nature of indeterminate FNA cytology results thus avoiding unnecessary surgical procedures. However the "suspicious" result of the Afirma GEC does not classify these indeterminate nodules further in determining a...

journal_title：Diagnostic cytopathology

authors： Roychoudhury S,Klein M,Souza F,Gimenez C,Laser A,Shaheen Cocker R,Chau K,Das K

更新日期：2017-04-01 00:00:00

abstract：:Human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is a unique form of carcinoma that largely arises from the tonsillar tissue in the oropharynx. These tumors often present with cervical lymphadenopathy resulting in a fine needle aspiration (FNA) biopsy. Use of the cytology specimen to de...

journal_title：Diagnostic cytopathology

authors： Bernadt CT,Collins BT

更新日期：2017-03-01 00:00:00

abstract：:This case involved a 69-year-old female who presented with irritative urinary voiding. Imaging studies showed an 18-cm uterine mass centering on the cervix and extending into the bladder. The Pap test slide demonstrated necrotic background and degenerative changes in single and grouped atypical "small round blue cells...

journal_title：Diagnostic cytopathology

authors： Yang G,Deisch J,Tavares M,Haixia Q,Cobb C,Raza AS

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:All malignant tumors may spread throughout the pleural, peritoneal, and pericardial cavities. The presence of tumor cells in serosal fluid is a poor prognostic indicator. It may be difficult to differentiate nuclear atypia of mesothelial cells due to injury of serosal surfaces from mesothelioma or malignant ...

journal_title：Diagnostic cytopathology

authors： Sadullahoglu C,Nart D,Veral A

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Diagnosis of hepatoblastoma (HBL) is based on characteristic clinical and radiological presentation, young age and marked elevation of serum α-fetoprotein (aFP). Fine needle aspiration (FNA) technique is successfully used in the diagnosis of hepatoblastoma. To evaluate the value of FNA in the diagnosis and s...

journal_title：Diagnostic cytopathology

authors： Vlajnic T,Brisse HJ,Aerts I,Fréneaux P,Cellier C,Fabre M,Klijanienko J

更新日期：2017-02-01 00:00:00

abstract：:Primary bladder signet-ring cell carcinoma (SRCC) is extremely rare and associated with an aggressive course. To our knowledge, we describe the first metastatic bladder SRCC identified in cerebrospinal fluid (CSF). A 68-year-old male with 1 year history of primary bladder SRCC with spinal metastasis presented with mul...

journal_title：Diagnostic cytopathology

authors： Lin DM,Park JW,Gattuso P

更新日期：2017-01-01 00:00:00

abstract：:Multiple myeloma (MM) with central nervous system (CNS) infiltration is uncommon and the diagnosis is more complicated than that of MM. Here we report two cases of CNS MM that was diagnosed by cerebrospinal fluid cytology examination. Cerebrospinal fluid cytology examination can help to detect malignant cells and immu...

journal_title：Diagnostic cytopathology

authors： Ren H,Zou Y,Zhao Y,Li J,Han X,He J,Guan H

更新日期：2017-01-01 00:00:00

abstract：:Papillary tumor of the pineal region (PTPR) is a rare neuroepithelial tumor of the pineal region of adults. We herein describe on a 34-year-old female the cytologic features of a PTPR studied using Diff-Quik stain. The patient presented hydrocephalia secondary to a pineal tumor. During surgery an intraoperative pathol...

journal_title：Diagnostic cytopathology

authors： Jiménez-Heffernan JA,Bárcena C,Gordillo C,Cañizal JM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Documenting the four molecular subtypes of breast carcinoma is significant as they determine response to therapy, disease free interval and survival. Our aim was to document the subtypes defined by immunohistochemistry (IHC) expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal...

journal_title：Diagnostic cytopathology

authors： Francis IM,Alath P,George SS,Jaragh M,Al Jassar A,Kapila K

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Urothelial carcinoma (UCC) of the bladder is the most common malignancy of the urinary tract. The performance of urine cytology (UCy) after radical cystectomy (RC) and urinary diversion is quite variable and there is no consensus regarding its role in post-treatment surveillance. The goal of this study is ...

journal_title：Diagnostic cytopathology

authors： Shanmugam V,Geraghty B,DeSimone RA,Hoda RS

更新日期：2016-12-01 00:00:00

abstract：:Primary pancreatic leiomyosarcomas are rare tumors of the pancreas that are usually diagnosed after resection or by biopsy. One case in the literature has utilized endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology. We report a second case of a primary pancreatic leiomyosarcoma that yielded diagnos...

journal_title：Diagnostic cytopathology

authors： Reyes MC,Huang X,Bain A,Ylagan L

更新日期：2016-12-01 00:00:00

abstract：:Granulosa cell tumors (GCT) of the ovary are low grade tumor with a potential ability of late pelvic recurrences and distant metastases. However, there is sparse literature on the cytopathologic features of metastatic granulosa cell tumors (MGCT). Between 2000 and 2014, eight cases of MGCT were diagnosed by FNA. Clini...

journal_title：Diagnostic cytopathology

authors： Harbhajanka A,Bitterman P,Reddy VB,Park JW,Gattuso P

更新日期：2016-12-01 00:00:00

abstract：:Columnar cell variant of papillary thyroid carcinoma (PTC) is an uncommon variant with an aggressive course as compared to classic papillary carcinoma. Cytologic diagnosis of these tumors is difficult due to absence of characteristic nuclear features of classic pattern of papillary carcinoma. We present a case of colu...

journal_title：Diagnostic cytopathology

authors： Verma R,Paul P

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:High-risk Human papillomavirus (HR-HPV)-associated head and neck squamous cell carcinoma (HNSCC) is a distinct epidemiologic and pathologic disease. The data of HR-HPV testing on fine-needle aspiration (FNA) materials of cervical lymph nodes in patients with metastatic HNSCC are limited. METHODS:We retrospe...

journal_title：Diagnostic cytopathology

authors： Hou Y,Chaudhary S,Shen R,Li Z

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:GATA-3 is a transcription factor involved in human tissue growth and differentiation. It is a potential marker for breast carcinoma origin in metastasis and predictive of good prognosis. We aim to evaluate the role of GATA3 in determining the breast origin of metastatic adenocarcinoma in malignant effusions ...

journal_title：Diagnostic cytopathology

authors： El Hag MI,Ha J,Farag R,El Hag AM,Michael CW

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Vaginal fine-needle aspiration (FNA) is infrequently performed to assess palpable lesions. We perform the first multi-institutional study to evaluate this procedure. METHODS:We retrospectively reviewed vaginal FNAs performed at two institutions for the past 27 years. Clinical, cytological and histological d...

journal_title：Diagnostic cytopathology

authors： Lin DM,Barkan GA,Chatt G,Park JW,Gattuso P

更新日期：2016-08-01 00:00:00

abstract：:Tumors of the head and neck are extremely diverse and a subset are poorly differentiated and difficult to classify. Recently, a new entity has been described with rhabdoid and/or plasmacytoid cytologic features and a characteristic genetic signature-inactivation of the SMARCB1 (INI-1) tumor suppressor gene. To date, o...

journal_title：Diagnostic cytopathology

authors： Allison DB,Bishop JA,Ali SZ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The essential of urine cytology for the diagnosis and the follow-up of urothelial neoplasia has been widely recognized. However, there are some cases in which a definitive diagnosis cannot be made due to difficulty in discriminating between benign and malignant. This study evaluated the practicality of nucle...

journal_title：Diagnostic cytopathology

authors： Tone K,Kojima K,Hoshiai K,Kumagai N,Kijima H,Kurose A

更新日期：2016-06-01 00:00:00

abstract：:We report a rare case of extranodal NK/T-cell lymphoma, nasal type of the uterine cervix that showed cytologic features mimicking cervical cancer. A 65-year-old woman presented with vaginal bleeding. Gynecological examination revealed a bulky tumor of the cervix. A conventional Papanicolaou-stained cervical smear show...

journal_title：Diagnostic cytopathology

authors： Omori M,Oishi N,Nakazawa T,Nakazawa K,Mitsumori T,Yuminamochi T,Kirito K,Hirata S

更新日期：2016-05-01 00:00:00

abstract：:Lipoblastoma is a peculiar variant of lipoma occurring almost exclusively during infancy and early childhood. It is found most commonly in the upper and lower extremities; less common sites are head and neck, trunk, mediastinum, and retroperitoneum. It has a greater predilection for boys and commonly presents as a slo...

journal_title：Diagnostic cytopathology

authors： Kalaivani Selvi S,Pradhan P,Rajesh NG,Gochhait D,Barwad A

更新日期：2016-05-01 00:00:00

abstract：:Chondroid syringoma (CS) is a rare benign adnexal tumor of the skin with a resemblance to pleomorphic adenoma of salivary gland, most commonly involving the head and neck region. In the present literature, reports of the cytologic appearance of CS are scarce as it is rarely encountered by fine needle aspiration (FNA)....

journal_title：Diagnostic cytopathology

authors： Rogers R,Zhou F,Grunes D,Shapiro RL,Bannan M,Simsir A,Leung A

更新日期：2016-04-01 00:00:00

abstract：:Mycobacterial infection, tuberculosis (TB) in particular, remains one of the world's deadliest communicable diseases in adults and particularly in children, in low and middle income countries. The combination of human immunodeficiency virus (HIV) and TB is often lethal with TB accounting for 25% of deaths in the HIV p...

journal_title：Diagnostic cytopathology

authors： Michelow P,Omar T,Field A,Wright C

更新日期：2016-03-01 00:00:00

abstract：:Clear cell hepatocellular carcinoma (CCHCC) is an uncommon morphologic variant of HCC and rarely invades into the main bile ducts. Here we describe a case of CCHCC that was diagnosed by bile duct brushing cytology. Liquid-based preparation of brushing specimen showed clusters of atypical epithelial cells with abundant...

journal_title：Diagnostic cytopathology

authors： Fu LY,Mitchell KA,Cai G

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Ubiquilin 2 (UBQLN2), an ubiquitin-related protein, is strongly expressed in urothelial carcinoma cells, in contrast to no or less expression in non-neoplastic cells; it protects cancer cells from reactive oxygen species (ROS)-induced cytotoxicity. In this study, we investigated whether UBQLN2 immunostaining...

journal_title：Diagnostic cytopathology

authors： Shimada K,Fujii T,Tatsumi Y,Anai S,Fujimoto K,Konishi N

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:This study aimed to assess solid thyroid nodule (STN) cases with discordant sonographic and cytological diagnoses and to compare the diagnostic indices of these modalities. METHODS:From January 2013 to December 2013, a single radiologist performed consecutive thyroid ultrasonography (US) and US-guided fine-...

journal_title：Diagnostic cytopathology

authors： Lee YJ,Kim DW,Park YM,Park HK,Jung SJ,Kim DH,Lee SM,Oh M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The triple test, i.e., cytology combined with clinical and radiological findings, is the goal for accurate assessment of palpable breast lesions. Because of the limitations of fine-needle aspiration cytology (FNAC), its utility has somewhat decreased nationwide. We have been using a combination of physical e...

journal_title：Diagnostic cytopathology

authors： Aker F,Gümrükçü G,Onomay BÇ,Erkan M,Gürleyik G,Kiliçoğlu G,Karagüllü H

更新日期：2015-12-01 00:00:00

abstract：:Synovial sarcomas (SS) of the head and neck region are extremely rare and arise in only 5% of cases. We present a case of secondary SS of the thyroid originally diagnosed as medullary carcinoma on fine needle aspiration (FNA). A 41-year-old man presented with several weeks of dysphonia and a left thyroid mass. FNA of ...

journal_title：Diagnostic cytopathology

authors： Murro D,Slade JM,Syed S,Gattuso P

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to clarify the diagnostic significance of the presence of intranuclear inclusions in clear cell carcinoma (CCC). MATERIALS AND METHODS:We analyzed 98 imprint specimens and 53 ascites specimens from 98 ovarian carcinoma cases [28 CCCs, 37 serous carcinomas (SCs), 22 endometrioid carc...

journal_title：Diagnostic cytopathology

authors： Naka M,Ohishi Y,Kaku T,Watanabe S,Tamiya S,Ookubo F,Kato K,Oda Y,Sugishima S

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration cytology (FNAC) of oral lesions has not been widely utilized for diagnosis due to rarity and diversity of lesions, peculiar anatomy of maxillofacial region, difficulty in aspirating these lesions, and limited experience. Aim of this study was to determine the role of FNAC in the diagno...

journal_title：Diagnostic cytopathology

authors： Goyal S,Sharma S,Diwaker P

更新日期：2015-10-01 00:00:00

abstract：:Epithelioid sarcoma is a rare mesenchymal neoplasm, with an as yet unidentified cell of origin. Two subtypes of epithelioid sarcoma, distal/classic and proximal/large cell type, are recognized in the literature; with the proximal-type having a lower incidence amongst the two. Here, we present a case of proximal-type e...

journal_title：Diagnostic cytopathology

authors： Pendse AA,Dodd LG

更新日期：2015-10-01 00:00:00

abstract：:Adult granulosa cell tumor (AGCT) is an uncommon neoplasm of the ovary with potential for aggressive behavior and late recurrence. The most important prognostic factor for AGCT is tumor stage. Thus, cytological assessment of pleural or ascitic fluids is crucial for initial staging and subsequent patient management. We...

journal_title：Diagnostic cytopathology

authors： Omori M,Kondo T,Yuminamochi T,Nakazawa K,Ishii Y,Fukasawa H,Hashi A,Hirata S

更新日期：2015-07-01 00:00:00

abstract：:Osteoblastomas are rare benign but sometimes aggressive primary bone tumors (1%), usually seen in males in the 2nd decade. Osteoblastomas, occurring in the spine, constitute a medical emergency due to impending cord compression. Hence a rapid and simple diagnostic modality, such as fine-needle aspiration (FNA) plays a...

journal_title：Diagnostic cytopathology

authors： Venugopal SB,Prasad S

更新日期：2015-03-01 00:00:00